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Original Article
A Clinical Characteristics of Systemic Candidiasis in Neonatal Intensive Care Unit : Comparison with Systemic Bacterial Infection
Jung Hwa Lim, Kyung Pil Park, Jin Kyung Kim, Heng Mi Kim
Clin Exp Pediatr. 2002;45(7):847-854.   Published online July 15, 2002
Purpose : Long term hospitalized infants in neonatal intensive care units(NICUs) are prone to systemic infection. It is important to differentiate systemic candidiasis from systemic bacterial infection early in the course. Thus, in this study, we have compared clinical characteristics of systemic candidiasis and systemic bacterial infection, in premature low birth weight infants. Methods : Retrospective chart review of the medical...
Changes in the Outcomes of Very Low Birth Weight Infants
Shung Shin Kim, Moon Hee Kim, Jae Won Shin, Sun Young Ko, Eun Kyung Lee, Yun Sil Chang, I Seok Kang, Won Soon Park, Mun Hyang Lee, Sang Il Lee, Heung Jae Lee
Clin Exp Pediatr. 2002;45(7):828-835.   Published online July 15, 2002
Purpose : The outcomes of infants weighing less than 1,500 gm(very low birth weight infant : VLBWI) reflect recent progress in neonatal intensive care. In this study, we analyzed changes over time in survival rate and morbidity of VLBWIs during the past seven years. Methods : A retrospective review of medical records was analyzed for VLBWIs admitted to the neonatal intensive...
The Prevalence of Obesity and Underweight in Adolescents in Incheon Area and the Relationship between Serum Cholesterol Level and Obesity
Myung Hyun Kim, Tae Wan Kim, Young Jin Hong, Byong Kwan Son, Soo Hwan Pai, Kyung Ja Chang, Soon Ki Kim
Clin Exp Pediatr. 2002;45(2):174-182.   Published online February 15, 2002
Purpose : The purpose of this study was to investigate the prevalence of obese and underweight adolescents in Incheon area and to examine the relationship between serum cholesterol level and obesity, then to assess the nutritional condition of adolescents. Methods : With a questionnaire regarding their demographic characteristics, blood samples were obtained from apparently healthy students aged 12 to 24 years...
Changes of Body Weight and Lipid Profiles According to Apolipoprotein E Polymorphism in Children with Antiepileptics
Seung Hee Jang, Eun Kyoung Choi, So Hee Eun, Sun Jun Kim
Clin Exp Pediatr. 2002;45(1):88-94.   Published online January 15, 2002
Purpose : Weight changes, especially weight gain, is a side effect of antiepileptics(especially valproate and carbamazepine). This may be sufficiently severe to cause noncompliance or to require the withdrawal of effective treatment. Unfortunately, the exact mechanism of weight change is not illustrated. Several reports and our experiment suggested that weight gain highly correlated with a familial tendency of obesity. The genetic makeup is a...
Factors Related to Weight Changes in Epileptic Children Treated with Vigabatrin
Sang-Nam Bae, Bong-Seok Choi, Sang-Ook Nam, Hee-Ju Park
Clin Exp Pediatr. 2001;44(11):1269-1277.   Published online November 15, 2001
Purpose : This study was undertaken to investigate factors related to weight changes in children treated with vigabatrin(VGB). Methods : We have analyzed mean weight standard deviation scores(SDS) retrospectively and interviewed 35 childhood epileptic patients attending Pusan National University Hospital on VGB monotherapy followed over 36 months. Putative risk factors including sex, age, duration of VGB administration, mean weight SDS...
The Role of Aldosterone on the Development of Renal Tubular Reabsorption in Low Birth Weight Infants
Byung Min Choi, Hoe Kyoung Koo, Jin Won Yook, Kyoung Bum Kim, Gi Young Jang, Moon Hee Kim, Kee Hwan Yoo, Young Sook Hong, Joo Won Lee, Soon Kyum Kim
Clin Exp Pediatr. 2001;44(11):1233-1242.   Published online November 15, 2001
Purpose : To determine the postnatal changes in aldosterone action on the renal tubular reabsorption in low birth weight(LBW) infants, we assessed the relation of the aldosterone concentrations to renal parameters during the first 10 days of life. Methods : Twenty LBW infants were evaluated and their gestational ages ranged from 32.4 to 39.3 weeks and their birth weights ranged from...
Growth and Neurodevelopmental Outcome at 15 Months of Corrected Age in Very Low Birth Weight Infants with Chronic Lung Disease
Seon Young Kim, Chang Yee Cho, Young Youn Choi
Clin Exp Pediatr. 2001;44(10):1112-1118.   Published online October 15, 2001
Purpose : This study was performed to compare the growth and neurodevelopmental outcome at 15 months of corrected age in very-low-birth weight infants between chronic lung disease(CLD) group and the control group. Methods : Very-low-birth-weight infants who were admitted and survived in the NICU(neonatal intensive care units) of Chonnam Univeristy Hospital from Jan. 1997 to Jan. 2000 were divided into...
The Detection of Chlamydia trachomatis Using Nested PCR in Prematurity and Delivery of Low Birth Weight Infant
Jae Ho Noh, Hye Kyung Lee, Han Jin Kim, Yong Sik Min, Kyeong Bae Park, Joon Soo Park, Young Chang Kim, Sung Ran Cho
Clin Exp Pediatr. 2001;44(8):875-880.   Published online August 15, 2001
Purpose : Polymerase chain reaction(PCR) has generally been more sensitive than traditional tests for the detection of Chlamydia trachomatis which has been a leading cause of sexually transmitted disease. We performed this study to find out if there is an association between C. trachomatis infection and low birth weight(LBW) or prematurity. Methods : The study included 98 premature or LBW infants...
Rehospitalization of Low-birth-weight Infants Who Were Discharged from NICU
Kyung Dan Choi, Young Suk Chae, Oh Kyung Lee
Clin Exp Pediatr. 1999;42(4):484-490.   Published online April 15, 1999
Purpose : We tried to compare normal term infants with low-birth-weight infants discharged from NICU by evaluating morbidity. So we studied rates of rehospitalization, reasons for rehospitalization and neonatal risk factors that affect rehospitalization of normal term infants and low-birth-weight infants discharged from NICU. Methods : This study was performed on 217 low-birth-weight infants discharged from NICU and 126 normal term...
Profile of Insulin, Growth Hormone and Insulin-like Growth Factors in Human Cord Blood According to Birth Weight
Hye Young Kim, Dae Yeol Lee, Soo Chul Cho
Clin Exp Pediatr. 1998;41(11):1484-1490.   Published online November 15, 1998
Purpose : Insulin-like growth factors(IGFs) are mitogenic peptides that are essential for fetal and maternal tissue growth during pregnancy. They circulate primarily with serum IGF-binding protein(IGFBP) which regulates the availability of IGFs to their specific target tissue. This study was performed to examine the relationships between birth weight and IGFs, insulin and growth hormone in the sera of cord blood...
A Study on the Factors Affecting Neonatal Birth Weight
Eun Young Hwang, Soo Beom Hwang, Jin Kil Par, Byung Mann Cho
Clin Exp Pediatr. 1998;41(9):1171-1179.   Published online September 15, 1998
Purpose : A low birth weight(LBW) rate is associated with perinatal morbidity and mortality. Many different factors are related to birth weight and LBW. This study examined the effects of various factors on birth weight. Methods : The study was conducted from January 1997 to August 1997 through direct interview with mother and medical history. Sample were drawn from 1,248 pairs...
The Study of Transplacental Transfer of Immunoglobulin G in Premature Infants
Sung Soo Moon, Yoon Ki Kang, Soo Chul Cho, Jung Soo Kim
Clin Exp Pediatr. 1998;41(6):747-753.   Published online June 15, 1998
Purpose : Premature infants have low serum immunoglobulin G(IgG) levels because IgG is transplacentally acquired, primarily after 32-34 weeks of gestational age. We studied the transplacental transfer of serum IgG in preterm infants. Methods : The IgG levels in the sera were measured by radial immunodiffusion method(Behring nephelometer, Germany). Results : There was a significant difference between IgG concentration and gestational age; the IgG concentration increased...
Postoperative Weight-Gain in Early Infants with Symptomatic Large Ventricular Septal Defect
Chang-Rang Kang, Hyang-Suk Yoon, Jong-Bum Choi, Soon-Ho Choi
Clin Exp Pediatr. 1997;40(12):1675-1680.   Published online December 15, 1997
Purpose : To investigate the postoperative patterns of weight-gain in early infants with ventricular septal defects(VSDs), we analyze 48 patients who received primary surgical closure of the symptomatic VSDs during 6 months of age in the period of 1993 through 1995. Methods : Forty-sixt infants met criteria for inclusion in the study. The mean follow up period was 14 months(3 to 36 months). Weight...
Influence of Phototherapy on Incidence of Patent Ductus Arteriosus in Very Low Birth W eight Infants
Hee Seok Kim, Ee Kyung Kim, Yun Kyoung Lee, Hee Eun Lee, Chan Hwu Park, Kyung Ran Park, Jun Dong Park, Beyong Il Kim, Woong Heum Kim, Jung-Hwan Choi, Yong Su Yun, Chong Ku Yun, Jeong Mi Lee
Clin Exp Pediatr. 1997;40(10):1410-1418.   Published online October 15, 1997
Purpose : Patent ductus arteriosus(PDA) is a common disease in very low birth weight infants(VLBWI). Hemodynamically significant PDA increases the morbidity and mortality of premature infants. Based on experimental model, light inhibits the constriction of immature piglet' s ductal rings. No specific mechanism adequately explains the effect of light on the relaxation of PDA. Several hypotheses, including activation of photosensitive metabolites, alterations in receptors, or...
Impact of Perinatal Risk Factors on Mental or Psychomotor Developmental Outcome of Very Low Birth W eight Infants
Eun Kyung Jin, Jong Uk Kim, Do Whan Kil, Oh Kyung Lee
Clin Exp Pediatr. 1997;40(9):1202-1209.   Published online September 15, 1997
Purpose : To determine which perinatal risk factors influence neurodevelopmental outcome, we try to investigate which perinatal risk factors are correlated with Baley mental or psychomotor developmental index using BSID-Ⅱ test(Baley Scales of Infant Development, Ⅱ) in long term follow up of very low birth weight who received neonatal intensive care. Methods : This study was performed on 56 very low birth weight infants with...
Growth and Neurodevelopmental Outcome on Very Low Birth Weight Infants During 2 Years
Eun Suk Kim, Jong Uk Kim, Oh Kyung Lee, Wan Soeb Kim
Clin Exp Pediatr. 1996;39(5):641-651.   Published online May 15, 1996
Purpose : By rapid development of neonatal intensive care from 1960, we are able to expect the long survival of the very low birth weight infants. But, there were high risk of poor growth, neurodevelopmental delay, deafness, and blindness in very low birth weight infants. So, it is important to follow-up after discharge. We try to compare normal term infants with...
Effect of Intravenous Immunoglobulin(IVIG) on Renal Function in Very Low Birth Weight Infants
Hwa Young Jang, Haeng Mi Kim
Clin Exp Pediatr. 1996;39(4):475-481.   Published online April 15, 1996
Purpose : This study was conducted to evaluate the effect of IVIG infusion on renal function in VLBW infants. IVIG has been proved quite safe in neonates given prophylactic and therapeutic doses. But nephrotoxicity is not recognized as adverse in IVIG therapy, only several previous adult cases have been noted. Methods : For a total of ten VLBW infants who had...
Erratum
Clinical Evaluation of Unmarried Maternal Neonates Admitted to NICU
Chang Weon Oh, Suk Hyun Lee, Kyoung Sim Kim, Ki Bok Kim
Accepted January 1, 1970  
Purpose : This study was done to see whether neonates born to unmarried mothers have higher rates of prematurity, low birth weight, perinatal morbidity and mortality than normal married group. Methods : 88 neonates of unmarried mothers who were admitted in our NICU during the 5-year period from January 1987 through December 1991 were evaluated, and as the control gro-up served...
Original Article
Study on Mean Birth Weight and Medical Care System at City Hospital
Young Mi Kim, Woon Ja Chung, Mi Kyung Kim, Shin Na Kim
Clin Exp Pediatr. 1995;38(1):27-35.   Published online January 15, 1995
Since Dongboo City Hospital cares patients with medicaid and poor socio-economic status in large percentage, we analized all the newborns delivered at the hospital from 1984 to 1992 by their birth weights, gender, gestational age and their Medical Care System. We found our babies' mean birth weight was lower than National standard mean birth weight of 1975 and 1985 (published...
Neurosonographic Abnormality; Periventricular echodensities and Intraventricular Hemorrhage: Usefulness in Predicting Neurodevelopmental Outcome in Very-Low-Birth-Weight, Preterm Infants
Dae Young Jang, Keun Wook Lee, Young Taek Jang, Oh Kyung Lee, Jin Ok Choi, Yeon Hi Kim
Clin Exp Pediatr. 1994;37(10):1376-1385.   Published online October 15, 1994
Serial neurosonographic examinations are routinely performed at frequent intervals during nursery couse of all preterm infants of very low-birth-weight who are admitted to the intensive care nursery of Presbyterian Medical Center from November 1,1900 to July 30, 1992. After discharge, the following survivors who had received periodic, serial scanning by means of cranial ultrasonography were longitudinally observed in an interdisciplinary neurodevelopmental...
Clinical Study on Very Low Birth Weight Infants
Sha Young Choi, Dae Young Jang, Oh Kyung Lee, Wan Seob Kim
Clin Exp Pediatr. 1994;37(5):628-635.   Published online May 15, 1994
Medical records of very low birth weight infants weighing less than 1500 grams at birth were reviewed and analyzed. One hundred and forty three infants who were admitted to neonatal intensive care unit of Presbyterian Medical Center, including those who were born and transferred from other hospitals, from January 1987 to December 1991 were examined and the following results were obtained; 1)...
Case Report
Furosemide-Induced Nephrocalcinosis in Very Low Birth Weight Infants
Clin Exp Pediatr. 1994;37(4):553-559.   Published online April 15, 1994
Renal calcifications are a recognized complication of furosemide therapy in premature infants. Particularly in infants with chronic lung disease, the use of this potent diuretic is associated with hypercalciuria, which may predispose the infant to medullary nephrocalcinosis and renal calculi. We experienced two cases of nephrocalcinosis in very low birth weight infants. One had bronchopulmonary dysplasia, pneumonia, patent ductus arteriosus,...
Original Article
The Significance of Nucleated Red Blood Cell Counts in Low Birth Weight Neonates
In Ho Song, Weon Kee Lee, Hye Lim Jung, Dong Hyuck Keum
Clin Exp Pediatr. 1993;36(11):1526-1533.   Published online November 15, 1993
We studied to assess the relationship between intrauterine growth retardation and the increased nucleated red blood cell counts (NRBC) in small for gestational age (SGA) and appropriate for gestational age (AGA) neonates with low birth weight. We also evaluated the nucleated red blood cell counts in low birth weight neonates who had either perinatal asphyxia or hyaline membrane disease (HMD)...
Clinical Observation for Low Birth Weight Infants
Hye Jin Lee, Soon Wan Kwon, Soon Ok Byun, Ji Sub Oh
Clin Exp Pediatr. 1993;36(7):928-935.   Published online July 15, 1993
Clinical observations were made on 338 low birth weight infants, who were delivered at Pusan Wallace Memorial Baptist Hospital, during the 3 year periods from 1989 to 1991. The results were as follows; 1) The incidence of LBWI was 5.6% and sex ratio was 1:1.09. Among them AGA was 62.7%. 2) Of all infants, 47.3% were in the birth weight range of 2251-2500...
Neurosonographic Diagnosis of Periventricular-Intaventricular Hemorrhage in Low Birth Weiht Infants
Hee Seok Koh, Dong Kyun Ryu, Young Tack Jang, Oh Kyung Lee, Jin Ok Choi
Clin Exp Pediatr. 1993;36(1):57-66.   Published online January 15, 1993
Periventricular-intraventricular hemorrhage (PV-IVH) is one of the most important neurologic lesion of the low birth weight infants. Serial neurosonographic examinations were performed in 113 low birth weight infants who were admitted to the neonatal internsive care unit of Presbyterian Medical Center from November 1, 1990 to July 31, 1991. The results were summarized as follows: 1) The incidence of PV-IVH in he study...
Evaluation of the Development of High Risk Low Birth Weight Infants Using Bayley Developmental Test
Chul Lee, Yil Seob Lee, Hyung Rae Cho, Dong Kwan Han
Clin Exp Pediatr. 1993;36(1):38-48.   Published online January 15, 1993
Forty two high risk low birth weight infants who had been admitted in neonatal intensive care unit at Yongdong Severance Hospital from August 1987 to July 1990 and followed up in the high risk infants follow-up clinic were studied for evaluation of their development using the Bayley developmental test at the age of 9 month (corrected age). The results obtained were...
Statistical Study on the Incidence and Mortality Rate of Low Birth Weight Infant
Sun-ae Kang, Jae-Kag Choi, Yeon-Kyun Oh
Clin Exp Pediatr. 1992;35(12):1690-1695.   Published online December 15, 1992
A statistical study on the icidence and mortality rate of low birth weight infant (LBW) was done on 11,406 newborns delivered at Wonkwang University Hospital during 9 years from Jan. 1,983 to Dec. 1,991. The results were as follows, 1) The incidence of LBW was 10.2%. 2) The incidence of LBW was higher than that of other hospital delivery (p<0.005). 3) Mortality rate of...
Postnatal change of Atrial natriuretic peptide in newborn Infants
Eun Sook Kim, Heng Mi Kim
Clin Exp Pediatr. 1992;35(9):1193-1197.   Published online September 15, 1992
Atrial natriuretic peptide(ANP)has been described as a part of the regulatory system of volume homeostasis. The role of ANP in postnatal volume hmestasis was investigated in 27 normal newborn infants during the early postnatal period. Plasma Mean plasma concentration of plasma ANP was 24.7¡¾13.8 pg/13.8pg/ml on the 1st day, 56.2¡¾60.0pg/ml on the 3-5th day and 35.0¡¾22.0pg/ml on the 7th day....
Clinical Observation on Very Low Birth Weight Infants
Jong Soo Lee, Mi Young Yeo, Byung Hak Lim, Sang Geel Lee
Clin Exp Pediatr. 1992;35(1):44-50.   Published online January 15, 1992
Charts of very low birth weight infants weighing less than 1500 gms at birth were revieved and the results were analyzed. Infants were 152 in numbers, admitted to nursery in Fatima Hospital from January 1986 to December 1989 including outborns. Results were as follow: 1) The incidence of very low birth weight was 5.78/1000 among 26270 newborn infants. 2) Maternal high...
Clinical and statistical observation for very low birth weight infants.
Sung Shin Park, Ji Hee Jung, Dong Hwan Lee, Sang Jhoo Lee
Clin Exp Pediatr. 1991;34(12):1629-1640.   Published online December 31, 1991
We made clinical and statistical observation of 90 very low birth weight infants who were admitted at Soonchunhyang university hospital during the 6 years period from January 1985 through December 1990. The result obtained were as follows: 1) The incidence of very low birth weight infant during 6 years period was 0.68%, and the mortality rate was 488/1000 very low birth weight infants. 2) There was no obvious...
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